298 research outputs found

    Economic results of the integrated crop-livestock systems implementation in degraded pastures in Pium, TO, Brazil.

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    In Pium, Tocantins state, Brazil, in 2012 Embrapa developed a technology transference project in partnership with the state?s rural extension service for the consolidation of low carbon emissions agriculture. The goal was to recover the degraded grasslands of the Trigueira farm (49°1'37.44"W and 10°24'58.84"S) with low cost using a crop-livestock system

    Financiamento da educação e remuneração docente na educação básica: uma abordagem a partir de planos de carreira, vencimentos e composição remuneratória em 2010

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    O texto apresenta aspectos conceituais, políticos e práticos da remuneração e carreira docentes como elementos de análise próprios da área de Financiamento em Educação. Estuda a estrutura da remuneração e da carreira, em diferentes Estados e municípios brasileiros, com o propósito de revelar o impacto das políticas de valorização docente. Entre outras, constata, em várias administrações públicas, a existência de valores de vencimento-base abaixo do piso salarial nacional e uma maior dispersão de vencimentos nas redes municipais de ensino. Conclui que, para definir e, sobretudo, para elevar o padrão remuneratório dos professores brasileiros, é imprescindível o aumento dos fundos destinados à Educação, além da pressão docente e da vontade política de gestores.

    Sobressemeadura de forrageiras na soja como alternativa de alto aporte de biomassa para o Sistema Plantio Direto.

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    O objetivo do trabalho foi avaliar a adição anual de biomassa de forrageiras implantadas em sobressemeadura na soja. Foi avaliada a safra 2015/2016 de um experimento objetivando longa duração, implantado em 2012 na estação experimental da Universidade Federal do Tocantins (Gurupi, TO)

    Silver colloidal nanoparticle stability: influence on Candida biofilms formed on denture acrylic

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    Our aim in this study was to evaluate how the chemical stability of silver nanoparticles (SNs) influences their efficacy against Candida albicans and C. glabrata biofilms. Several parameters of SN stability were tested, namely, temperature (50ºC, 70ºC, and 100ºC), pH (5.0 and 9.0), and time of contact (5 h and 24 h) with biofilms. The control was defined as SNs without temperature treatment, pH 7, and 24 h of contact. These colloidal suspensions at 54 mg/L were used to treat mature Candida biofilms (48 h) formed on acrylic. Their efficacy was determined by total biomass and colony-forming unit quantification. Data were analyzed using analysis of variance and the Bonferroni post hoc test (=0.05). The temperature and pH variations of SNs did not affect their efficacy against the viable cells of Candida biofilms (P > 0.05). Moreover, the treatment periods were not decisive in terms of the susceptibility of Candida biofilms to SNs. These findings provide an important advantage of SNs that may be useful in the treatment of Candida-associated denture stomatitis.We thank Dr David Williams, Cardiff University, Cardiff, UK, for providing the strain 324LA/94. The authors also thank Sao Paulo Research Foundation (FAPESP, process 2009/15146-5), Brazil, for supporting the work of D. R. M. The authors are indebted to Laboratorio Interdisciplinar de Eletroquimica e Ceramica, Federal University of Sao Carlos, Brazil, in the name of Andressa Kubo, for preparing and characterizing the colloidal suspensions of silver nanoparticles

    Different Infective Forms Trigger Distinct Immune Response in Experimental Chagas Disease

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    Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface. Thus, aspects related to the variability that the forms of T. cruzi interacts with host cells may lead to fundamental implications on the immune response against this parasite and, consequently, the clinical evolution of Chagas disease. We have shown that BT infected mice presented higher levels of parasitemia during all the acute phase of infection. Moreover, the infection with either MT or BT forms resulted in increased levels of total leukocytes, monocytes and lymphocytes, specifically later for MT and earlier for BT. The infection with BT forms presented earlier production of proinflammatory cytokine TNF-α and later of IFN-γ by both T cells subpopulations. This event was accompanied by an early cardiac inflammation with an exacerbation of this process at the end of the acute phase. On the other hand, infection with MT forms result in an early production of IFN-γ, with subsequent control in the production of this cytokine by IL-10, which provided to these animals an immunomodulatory profile in the end of the acute phase. These results are in agreement with what was found for cardiac inflammation where animals infected with MT forms showed intense cardiac inflammation later at infection, with a decrease in the same at the end of this phase. In summary, our findings emphasize the importance of taking into account the inoculums source of T. cruzi, since vectorial or transfusional routes of T. cruzi infection may trigger distinct parasite-host interactions during the acute phase that may influence relevant biological aspects of chronic Chagas disease
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